KEY TAKEAWAY POINTS

The clinical relevance of visual fields has progressed over time, and is a relevant functional indicator of the status of a patient’s glaucoma

Standardized automated perimetry has been an essential tool to help best guide disease management for glaucoma patients

Several models beyond those found within standardized automated perimetry have attempted to better predict progression of visual field loss

A hierarchical model that has the ability to describe the rates of progression between groups as well as at Garway-Heath clusters and point locations, and that accounts for censoring of 0 dB readings may provide practical advantages and can identify deeper insight into identified patterns of visual field loss

A model by Montesano et al that was used in the Laser in Glaucoma and Ocular Hypertension Trial (LiGHT) and Treatment of Advanced Glaucoma Study (TAGS) was applied in a retrospective, post-hoc manner to the 5-year visual field data of the HORIZON Trial

This post-hoc analysis revealed a difference in the rate of progression between groups, but it was apparent that there were a greater number of fast progressors in the cataract surgery-alone group that could account for these differences

A number of limitations to this analysis must be understood to interpret these findings within context