- Dry Eye
A Novel Approach To Increasing Natural Tear Production In Dry Eye Disease
Mar 19, 2026
Data from the pivotal COMET clinical trials reveal how the first topical ocular neuromodulator approved for DED—TRYPTYR (acoltremon ophthalmic solution) 0.003%—delivers a rapid and lasting increase in natural tear production.
John Hovanesian, MD
Marjan Farid, MD
Nate Lighthizer, OD
Selina McGee, OD