KEY TAKEAWAY POINTS

The determinates of flow rate in vitreoretinal procedures are complex, due to the unpredictable nature of the vitreous and how various parameters interact with each other.

An increasing cut rate contributes to higher vitreous flow due to higher fragmentation of vitreous but is met by physical limits.

Cutter designs can be modified to overcome these limits, such as port and blade optimizations.

Modern vitrectomy cutters, at their highest available cut rates, provide high vitreous flow rates along with lower tractional forces during vitreoretinal procedures.