KEY TAKEAWAY POINTS

Microsurgery involves the surgeon working at, or just beyond, the threshold of human dexterity as well as beyond the threshold of sensory feedback needed for good control of an instrument

The diameter of microsurgical instrument handles as well as the applied actuation forces can affect the ease or difficulty of their use

Surgical instrument handles have been optimized to provide the tool characteristics and attributes important to multiple surgeons from different regions, genders, experience levels, and hand sizes

By building upon the favorable 360-degree angular orientation, optimized handle diameter and actuation forces, along with increased instrument stiffness, can favorably affect a microsurgical instrument handle’s ease of use in cases requiring fine instrument control